Search Result

Search Results for " il 8 "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T27695	JTE-607	JTE-607 dihydrochloride,JTE-607 HCl	Cysteine Protease
	JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.		Cysteine Protease
T11179	Elubrixin	SB-656933	IL Receptor , CXCR
	Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...		IL Receptor , CXCR
T1497	Liranaftate	Piritetrate,M-732	Antifungal
	Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...		Antifungal
T0089	Cetirizine dihydrochloride	P071,UCB P071,Cetirizine DiHCl	Histamine Receptor
	Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona...		Histamine Receptor
T3185	R112	(E)-Elafibranor	Syk
	R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.		Syk
T2036	6-OAU	GTPL5846	GPR
	6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.		GPR
T83712	Interleukin-8 (54-72) (human) TFA	IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)
	Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical v...
T6823	E3330		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
	E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
T1955	SB225002		CXCR
	SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.		CXCR
T5193	Danirixin	GSK1325756	CXCR
	Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).		CXCR
T9656	AP-1/NF-κB activation inhibitor 1		NF-κB , DNA/RNA Synthesis
	AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation in...		NF-κB , DNA/RNA Synthesis
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
T24816	SP-100030	SP100030,SP 100030	NF-κB
	SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ...		NF-κB
T76727	Teprotumumab	R 1507,HZN 001	TSH Receptor , IGF-1R
	Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te...		TSH Receptor , IGF-1R
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T21644L	AF 12198 Acetate	AF 12198 Acetate (185413-30-3 Free base)	IL Receptor
	AF 12198 Acetate is a novel low molecular weight antagonist of IL-1		IL Receptor
T6488	Epinastine hydrochloride	Alesion,Epinastine HCl,WAL-801CL HCl,Elestat	5-HT Receptor , Histamine Receptor
	Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.		5-HT Receptor , Histamine Receptor
TP1516L	C-Reactive Protein (CRP) 77-82 acetate	C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)	Others
	C-Reactive Protein (CRP) 77-82 acetate is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactiv...		Others
T27967	M199
	M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.
T27708	K-14585
	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone incre...
T25469	GSK223	GSK 223,GSK-223
	GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.
T70001	Pyrazinib
	Pyrazinib is a novel inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, significantly inhibiting the secretion of il-6, il-4, il-8 and il-13 cytokines from in oac radioresist...
T35450	α-GalCer analog 8	α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-load...
T63088	NOD2 antagonist 1
	NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23μM). NOD2 antagonist 1 in THP-1 cells repress Muramyl DiDP (MDP) -induced IL-8 secretion. NOD2 antagonist 1 in PBMCs cells inhibits...
T80561	Atrosab
	Atrosab, a humanized IgG1 anti-TNFR1 antibody, exhibits antagonistic properties by inhibiting TNF-induced apoptosis and reducing the production of IL-6 and IL-8. It is utilized for research on inflammatory diseases [1].
TP2035	FSL-1	FSL 1
	TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells.
T71048	Tacrolimus anhydrous 8-epimer
	Tacrolimus anhydrous 8-epimer is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-...
T36623	Antileukinate
	Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutro...
T41189	AY 254
	AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-woun...
T80469	Citrullinated LL-37 1cit
	Citrullinated LL-37 1cit, a modified LL-37 peptide, retains the antiviral properties of its parent compound against human rhinovirus and exhibits antibacterial activity against S. aureus. Furthermore, it diminishes the R...
T2968L	Hyodeoxycholic acid sodium salt	Sodium hyodeoxycholate,HDCA sodium
	Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces strong cytotoxicity, apoptosis, and IL-8 sy...
T36198	Avenanthramide-C methyl ester
	Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits t...
T78175	JAK-IN-25		JAK
	JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. It also demonstrates an IC50 of 28 nM against human whole blood IL-12 (HEB IL-1...		JAK
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3...
T76242	MMI-0100
	MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression w...
T60366	Epinastine
	Epinastine (WAL801), a potent, selective, and orally-active antihistamine and mast cell stabilizer, functions as a histamine H1 receptor antagonist. It also inhibits IL-8 release from human eosinophils, showcasing antial...
T69599	ABT-510
	ABT-510 is synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascul...
T80470	Citrullinated LL-37 2cit
	Citrullinated LL-37 2cit, a modified version of the LL-37 peptide, attenuates the antiviral efficacy of LL-37 against Human Rhinovirus (HRV) at a concentration of 10 μg/mL and diminishes its antibacterial properties. Fur...
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and...
T62221	NLRP3-IN-8
	NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 1...
T76869	Lirentelimab
	Lirentelimab (AK002), a humanized IgG1 monoclonal antibody, specifically targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). It promotes apoptosis in IL-5-activated eosinophils and suppresses IgE-mediated activation ...
T61885	Sulconazole
	Sulconazole is an imidazole compound with effective antifungal effect. Sulconazole vs. NF- κ B/IL-8 signal pathway has blocking effect and inhibiting effect on the formation of cancer stem cells (CSC). Sulconazole has in...
T83698	Cathelicidin-2 (128-153) (chicken) TFA	Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
	Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide derived from amino acids 128-153 of chicken CATH-2, demonstrating activity against pathogens such as E. coli, S. aureus, S. enteritidis, and B. globi...
T83798	8-bromo NAD+ sodium	8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
	8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in in...
T41121	Elubrixin tosylate	SB-656933 tosylate,Elubrixin tosylate
	Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b ...
T38360	NBC 19
	Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release. Baldwin et al (2017) Boron-Based Inhibitors of the NLRP3 Inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355 \|Red...
T37564	C4 Ceramide (d18:1/4:0)	C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
	C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used...
T35864	T-5342126
	T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isola...
T21633	N-3-oxo-dodecanoyl-L-Homoserine lactone
	N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule, is synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2]. This regulatory mechanism facilitates bacteria...

Compounds

Ossirene

T6761

Synonym: AS101

Target: IL Receptor, Caspase, Interleukin

JTE-607

T27695

Synonym: JTE-607 dihydrochloride,JTE-607 HCl

Target: Cysteine Protease

Elubrixin

T11179

Synonym: SB-656933

Target: IL Receptor, CXCR

Liranaftate

T1497

Synonym: Piritetrate,M-732

Target: Antifungal

Cetirizine dihydrochloride

T0089

Synonym: P071,UCB P071,Cetirizine DiHCl

Target: Histamine Receptor

R112

T3185

Synonym: (E)-Elafibranor

Interleukin-8 (54-72) (human) TFA

T83712

Synonym: IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)

Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis

AP-1/NF-κB activation inhibitor 1

T9656

Synonym:

Target: NF-κB, DNA/RNA Synthesis

Boc-Asp(OMe)-fluoromethyl ketone

T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Caspase

SP-100030

T24816

Synonym: SP100030,SP 100030

Target: NF-κB

Teprotumumab

T76727

Synonym: R 1507,HZN 001

Target: TSH Receptor, IGF-1R

GSK717

T38361

Synonym:

Target: IL Receptor, NOD

AF 12198 Acetate

T21644L

Synonym: AF 12198 Acetate (185413-30-3 Free base)

Target: IL Receptor

Epinastine hydrochloride

T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,Elestat

Target: 5-HT Receptor, Histamine Receptor

C-Reactive Protein (CRP) 77-82 acetate

TP1516L

Synonym: C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)

Synonym: GSK 223,GSK-223

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

Tacrolimus anhydrous 8-epimer

Citrullinated LL-37 1cit

T80469

Synonym:

Target:

Hyodeoxycholic acid sodium salt

T2968L

Synonym: Sodium hyodeoxycholate,HDCA sodium

Target:

Avenanthramide-C methyl ester

Citrullinated LL-37 2cit

Cathelicidin-2 (128-153) (chicken) TFA

T83698

Synonym: Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)

Target:

8-bromo NAD+ sodium

T83798

Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

Target:

Elubrixin tosylate

T41121

Synonym: SB-656933 tosylate,Elubrixin tosylate

C4 Ceramide (d18:1/4:0)

T37564

Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

N-3-oxo-dodecanoyl-L-Homoserine lactone

T21633

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TN1520	Isoforskolin	Coleonol B	IL Receptor , TNF
	Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.		IL Receptor , TNF
T5680	Aloin(mixture of A&B)		MMP , IL Receptor , Antibacterial , Antifungal
	ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.		MMP , IL Receptor , Antibacterial , Antifungal
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...		IL Receptor
T2791	Pectolinarin		Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
	Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
TN1154	Nepetin	6-Methoxyluteolin	Calcium Channel , Histamine Receptor
	Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.		Calcium Channel , Histamine Receptor
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
T75674	Pedunculagin
	Pedunculagin, a potent 5α-reductase type 1 inhibitor, effectively inhibits the production of nitric oxide (NO), IL-6, and IL-8 while also decreasing the protein expression of 5α-reductase. Additionally, it exhibits anti-...
TN5238	Viscidulin II		IL Receptor , TNF
	Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of ...		IL Receptor , TNF
T75694	Lacto-N-neotetraose
	Lacto-N-neotetraose (LNnT), an endogenous metabolite, inhibits TNF-α-induced IL-8 secretion in immature epithelial cells, exhibits anti-inflammatory activity, and enhances wound closure [1] [2] [4].
T37751	Streptazolin
	Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes. It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin ...
TN4471	Lysicamine		IL Receptor , Antifection
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and a...		IL Receptor , Antifection

Natural Products

Isoforskolin

TN1520

Synonym: Coleonol B

Target: IL Receptor, TNF

Aloin(mixture of A&B)

T5680

Synonym:

Target: MMP, IL Receptor, Antibacterial, Antifungal

Berberrubine chloride

T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

Nepetin

TN1154

Synonym: 6-Methoxyluteolin

Target: Calcium Channel, Histamine Receptor

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Auraptene

T4115

Synonym: 7-geranyloxycoumarin

Target: IL Receptor, TNF

Target: IL Receptor, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5.
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)	Human	E. coli
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5.
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5.
TMPY-02886	IL-17A Protein, Human, Recombinant	Human	E. coli
	IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-00470	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque...
TMPY-00053	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant	Human	E. coli
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1.
TMPY-02900	IL-17A Protein, Mouse, Recombinant	Mouse	E. coli
	IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386.
TMPK-00480	IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL...
TMPY-00755	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPY-00753	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.6 kDa and the accession number is A0A024RDA5.
TMPK-01036	IL-17A Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPK-01037	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPK-00975	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1.
TMPK-01266	IL-17A Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293 Cells
	IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
TMPJ-01444	IL-17A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ...
TMPK-01045	IL-20RA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferati...
TMPY-03568	IL-17A Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552.
TMPY-04332	IL-17A Protein, Human, Recombinant (T26A, His)	Human	Baculovirus Insect Cells
	IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552.
TMPY-05183	IL-17A Protein, Human, Recombinant, Biotinylated	Human	E. coli
	IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-01054	IL-20RA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-20RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9UHF4-1.
TMPY-00280	IL-20RA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-20RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9UHF4-1.
TMPH-00376	IL-8/CXCL8 Protein, Chicken, Recombinant	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPY-03022	IL-8/CXCL8 Protein, Canine, Recombinant	Canine	E. coli
	IL-8/CXCL8 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.2 kDa and the accession number is P41324.
TMPY-03480	IL-8/CXCL8 Protein, Rhesus, Recombinant	Rhesus	E. coli
	IL-8/CXCL8 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.3 kDa and the accession number is P67813.
TMPH-00375	IL-8/CXCL8 Protein, Chicken, Recombinant (His)	Chicken	E. coli
	May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPH-01559	IL-26 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPH-01560	IL-26 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPY-04123	CEACAM1 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPK-00405	IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated	Human	HEK293 Cells
	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr...
TMPJ-01361	Siglec-8 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory mo...
TMPJ-01237	IL-17D Protein, Human, Recombinant	Human	E. coli
	The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable s...
TMPJ-01060	CXCL6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines...
TMPJ-00060	IL-25/IL17E Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a con...
TMPY-03853	DCBLD2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that...
TMPJ-00760	CXCL7 Protein, Human, Recombinant	Human	E. coli
	Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domai...
TMPJ-01187	Siglec-E Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also ...
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-00828	Tau-F Protein, Human, Recombinant	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPJ-00808	CD45RA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-01330	CD299 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-S...
TMPH-01705	Mucin-1/MUC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPY-00717	CEACAM1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.

IL-8/CXCL8 Protein, Human, Recombinant (His)

TMPY-04726

Species: Human

Expression System: P. pastoris (Yeast)

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)

TMPY-00472

Species: Human

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)

TMPY-00754

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant

TMPY-02886

Species: Human

Expression System: E. coli

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

TMPY-00470

Species: Human

Expression System: HEK293 Cells

IL-17 Protein, Mouse, Recombinant (His)

TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant

TMPY-00053

Species: Human

Expression System: E. coli

IL-17A Protein, Mouse, Recombinant

TMPY-02900

Species: Mouse

Expression System: E. coli

IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)

TMPK-00480

Species: Cynomolgus

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)

TMPY-00755

Species: Human

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)

TMPY-00753

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi)

TMPK-01036

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-01037

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00975

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His & Avi)

TMPK-01266

Species: Cynomolgus

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His)

TMPJ-01444

Species: Cynomolgus

Expression System: HEK293 Cells

IL-20RA Protein, Mouse, Recombinant (hFc)

TMPK-01045

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (His)

TMPY-03568

Species: Human

Expression System: P. pastoris (Yeast)

IL-17A Protein, Human, Recombinant (T26A, His)

TMPY-04332

Species: Human

Expression System: Baculovirus Insect Cells

IL-17A Protein, Human, Recombinant, Biotinylated

TMPY-05183

Species: Human

Expression System: E. coli

IL-20RA Protein, Human, Recombinant (His)

TMPY-01054

Species: Human

Expression System: HEK293 Cells

IL-20RA Protein, Human, Recombinant (hFc)

TMPY-00280

Species: Human

Expression System: HEK293 Cells

IL-8/CXCL8 Protein, Chicken, Recombinant

TMPH-00376

Species: Chicken

Expression System: E. coli

IL-8/CXCL8 Protein, Canine, Recombinant

TMPY-03022

Species: Canine

Expression System: E. coli

IL-8/CXCL8 Protein, Rhesus, Recombinant

TMPY-03480

Species: Rhesus

Expression System: E. coli

IL-8/CXCL8 Protein, Chicken, Recombinant (His)

TMPH-00375

Species: Chicken

Expression System: E. coli

LTBR Protein, Mouse, Recombinant (hFc)

TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

IL-26 Protein, Human, Recombinant (His)

TMPH-01559

Species: Human

Expression System: P. pastoris (Yeast)

IL-26 Protein, Human, Recombinant (His & Trx)

TMPH-01560

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His & hFc)

TMPY-04123

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated

TMPK-00405

Species: Human

Expression System: HEK293 Cells

Siglec-8 Protein, Human, Recombinant (mFc)

TMPJ-01361

Species: Human

Expression System: HEK293 Cells

IL-17D Protein, Human, Recombinant

TMPJ-01237

Species: Human

Expression System: E. coli

CXCL6 Protein, Human, Recombinant (His)

TMPJ-01060

Species: Human

Expression System: HEK293 Cells

IL-25/IL17E Protein, Human, Recombinant (His)

TMPJ-00060

Species: Human

Expression System: HEK293 Cells

DCBLD2 Protein, Human, Recombinant (His)

TMPY-03853

Species: Human

Expression System: HEK293 Cells

CXCL7 Protein, Human, Recombinant

TMPJ-00760

Species: Human

Expression System: E. coli

Siglec-E Protein, Mouse, Recombinant (hFc)

TMPJ-01187

Species: Mouse

Expression System: HEK293 Cells

NT5C3A/NT5C3 Protein, Human, Recombinant

TMPY-02893

Species: Human

Expression System: E. coli

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

TMPY-00668

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

TMPY-06707

Species: Human

Expression System: HEK293 Cells

Tau-F Protein, Human, Recombinant

TMPJ-00828

Species: Human

Expression System: E. coli

CD45RA Protein, Human, Recombinant (His)

TMPJ-00808

Species: Human

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (His & Flag)

TMPJ-01330

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (His)

TMPH-01705

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His)

TMPY-00717

Species: Human

Expression System: HEK293 Cells

Cat No.	Product Name
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

NF-κB Signaling Compound Library

L3800

Compounds: 729

Chemokine Inhibitor Library

L7600

Compounds: 59